Rival QB injury puts Jimmy Garoppolo back on 49ers fans’ radar

There was anticipation throughout 2024 and into the 2025 offseason that the San Francisco 49ers might face their former quarterback, Jimmy Garoppolo, after he signed with the NFC West rival Los Angeles Rams. However, this scenario required Rams starter Matthew Stafford to be unavailable, which didn't happen in 2024 as Stafford played and beat the 49ers twice.

The situation might change in 2025 due to Stafford currently dealing with back issues. This has led to Stafford resting during training camp and Garoppolo receiving significant first-team practice reps. Rams head coach Sean McVay stated Stafford's status is "week to week," with the goal being readiness for the regular season opener on September 7th. McVay emphasized wanting to avoid setbacks, leaving the door open for Garoppolo to start as QB1 when the Rams host the 49ers in Week 5 on Thursday Night Football.

The potential matchup is considered "juicy" due to the acknowledged awkwardness between Garoppolo and the 49ers since his departure. Garoppolo has taken subtle shots at his former team, despite having his best career years there, leading to a drop in his perceived value among fans. The article suggests 49ers defensive coordinator Robert Saleh would relish deploying his defense against Garoppolo, recalling his tendencies to throw interceptions over the middle.

This scenario ultimately hinges on Stafford's health. While the Rams might be exercising extreme caution, any setbacks with Stafford's back injury would significantly increase the likelihood of a Garoppolo versus 49ers showdown.